Ascoff 100ml in Kenya

ASCOFF COUGH EXPECTORANT AND BRONCHODILATOR is a 100ml syrup manufactured in Kenya by Sphinx Pharmaceuticals Ltd. This multi-component cough syrup is formulated to provide comprehensive relief for upper respiratory tract infections, particularly those associated with the production of heavy mucus and difficulty breathing. It combines the actions of a bronchodilator, a mucolytic, an expectorant, and a soothing agent.

Each 5ml of Ascoff syrup contains:

• Salbutamol 2mg: A bronchodilator.
• Bromhexine 4mg: A mucolytic.¹

   

• Guaifenesin 100mg: An expectorant.²

   

• Menthol 1mg: A soothing agent.³

   

The combined action of these ingredients helps to loosen mucus, open up the respiratory tract, and enable easy coughing out of sputum, thus facilitating easier breathing.

Unpacking the Formulation: Key Components and their Mechanisms

Ascoff syrup provides multi-symptom relief through the synergistic action of its active ingredients:⁴

• Salbutamol (2mg per 5ml):
  • Class: Short-acting Beta-2 Adrenergic Agonist (SABA) / Bronchodilator.
  • Mechanism of Action: Salbutamol selectively stimulates beta-2 adrenergic receptors primarily found in the smooth muscles of the bronchi (airways).⁵ This stimulation leads to the relaxation of these muscles, causing bronchodilation (widening of the airways).⁶ By opening the respiratory tract, salbutamol eases breathing difficulties, especially in conditions where bronchospasm (narrowing of airways) is present, such as asthma or bronchitis.⁷

     

• Bromhexine (4mg per 5ml):
  • Class: Mucolytic.
  • Mechanism of Action: Bromhexine works by breaking down the complex mucopolysaccharide fibers in mucus. This action reduces the viscosity (thickness) and adhesiveness of mucus in the respiratory passages, making it thinner and less sticky.⁸ This facilitates the easier movement and clearance of mucus from the airways.

     

• Guaifenesin (100mg per 5ml):
  • Class: Expectorant.⁹

     

  • Mechanism of Action: Guaifenesin works by increasing the volume and decreasing the viscosity of secretions in the respiratory tract.¹⁰ It irritates the gastric mucosa, which then stimulates vagal nerve endings and triggers a reflex secretion of fluid from the bronchial glands. This increased fluid content helps to loosen and thin bronchial secretions, making coughs more productive and easier to expel sputum.

     

• Menthol (1mg per 5ml):
  • Class: Mild Local Anesthetic, Decongestant, Soothing Agent.
  • Mechanism of Action: Menthol provides a cooling and soothing sensation that can temporarily relieve irritation in the throat and air passages.¹¹ It also has mild decongestant properties by stimulating cold receptors in the nasal and pharyngeal mucosa, giving a sensation of clear breathing.

     

The combination addresses both airway constriction and mucus congestion, making coughs more effective and breathing more comfortable.

Addressing Health Concerns and User Needs

ASCOFF syrup is formulated to address key symptoms of respiratory infections:

• Productive Coughs: Helps individuals with chesty coughs that produce heavy and thick mucus.¹²

   

• Difficulty Breathing: The bronchodilator component opens airways, easing shortness of breath and wheezing.
• Mucus Congestion: Effectively thins and loosens stubborn mucus, making it easier to clear from the lungs and airways.¹³

   

• Throat Irritation: Menthol provides a soothing effect on irritated throat and respiratory passages.¹⁴

   

• Associated with URTI: Indicated for upper respiratory tract infections where these symptoms are prevalent.

Identifying Indications for Use

ASCOFF COUGH EXPECTORANT AND BRONCHODILATOR is indicated for:

• Upper respiratory tract infections (URTI) associated with:
  • Production of heavy, thick, or tenacious mucus.
  • Bronchospasm or narrowing of airways leading to difficulty breathing (e.g., in bronchitis, asthmatic bronchitis, or other obstructive airway diseases where mucus retention is a problem).
  • Congested coughs where sputum is difficult to expel.
• Conditions requiring simultaneous bronchodilation, mucolysis, and expectoration.

Primary Uses

The primary uses of ASCOFF syrup include:

• Relieving bronchospasm and opening airways for easier breathing.
• Thinning and loosening heavy mucus in the respiratory tract.
• Promoting productive coughing to effectively expel sputum.
• Soothing irritated throat and airways.
• Managing symptoms of respiratory infections with mucus congestion and airway narrowing.¹⁵

   

Understanding Potential Side Effects and Critical Precautions

As Ascoff contains Salbutamol, a bronchodilator, it has specific side effects related to sympathetic nervous system stimulation, in addition to common side effects from other ingredients.

Common Side Effects (Mostly from Salbutamol)

• Tremors: Fine tremor of the hands, especially common.
• Nervousness or restlessness.
• Headache.
• Palpitations or rapid heartbeat (tachycardia).
• Muscle cramps.
• Nausea or upset stomach (from guaifenesin or bromhexine).¹⁶

   

• Dizziness.
• Drowsiness (less common, but possible).

Less Common but More Serious Side Effects (Seek medical attention)

• Paradoxical Bronchospasm: A sudden worsening of breathing difficulties immediately after taking the syrup. If this occurs, discontinue immediately and seek medical help.
• Serious Allergic Reactions: Rash, itching, swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.¹⁷ Seek immediate medical attention.

   

• Hypokalemia: Low potassium levels, which can manifest as muscle weakness, cramps, or irregular heartbeats.¹⁸ This is more likely with high doses or in susceptible individuals.

   

• Arrhythmias: Irregular heartbeats, especially if you have pre-existing heart conditions.
• Chest pain.

Critical Safety Warnings and Precautions for Ascoff Syrup

• Pre-existing Conditions: Inform your doctor about any pre-existing medical conditions, especially:
  • Heart conditions: Arrhythmias, high blood pressure, coronary artery disease.
  • Thyroid problems (hyperthyroidism).
  • Diabetes: Salbutamol can transiently increase blood glucose levels.¹⁹

     

  • Seizure disorders.
  • Kidney or liver impairment.
  • Ulcers (caution with bromhexine).²⁰

     

• Drug Interactions: Inform your doctor or pharmacist about all other medications you are taking, including over-the-counter drugs, herbal remedies, and supplements. Significant interactions include:
  • Beta-blockers (e.g., propranolol): Can block the effects of salbutamol.²¹

     

  • MAOIs and TCAs (antidepressants): Can potentiate the cardiovascular effects of salbutamol.²²

     

  • Diuretics: Can increase the risk of hypokalemia with salbutamol.
  • Other cough/cold medications: Avoid concurrent use of other products containing similar ingredients to prevent overdose.
• Dosage Adherence: Do not exceed the recommended dose or frequency. Higher doses do not provide more relief and significantly increase the risk of side effects.
• Not for Chronic Cough: This syrup is intended for acute, productive coughs.²³ If the cough persists for more than 7 days, recurs, or is accompanied by fever, rash, or persistent headache, consult a doctor as these could be signs of a serious condition.

   

• Asthma/COPD: While it contains a bronchodilator, Ascoff is not a primary or sole treatment for severe acute asthma attacks or chronic obstructive pulmonary disease (COPD). Patients with these conditions require specific, prescribed inhalers or medications.
• Driving/Operating Machinery: Salbutamol can cause tremors or dizziness.²⁴ Exercise caution when driving or operating machinery until you know how you react to the medication.

   

• Pregnancy and Breastfeeding: Consult your doctor before using during pregnancy or breastfeeding. The safety of all components in these situations should be assessed by a healthcare professional.
• Alcohol: Avoid alcohol consumption while taking this syrup as it can exacerbate drowsiness and other side effects.²⁵

   

Recommended Dosage and Administration Guidelines

• Dosage: Dosing will vary based on age and weight.
  • Adults and Children 12 years and above: Typically 10ml (two teaspoonfuls) 3-4 times daily.
  • Children 6-12 years: Typically 5ml (one teaspoonful) 3-4 times daily.²⁶

     

  • Children under 6 years: Dosage must be determined by a physician.
  • Always use the provided measuring spoon or cup.
  • Always follow your doctor’s specific instructions or the directions on the product packaging. Do not exceed the maximum daily dose.
• Administration:
  • Shake the bottle well before each use.
  • Take the syrup by mouth.
  • Can be taken with or without food.
• Duration of Treatment: Use only for as long as symptoms persist, typically for a few days. If symptoms do not improve or worsen, consult a doctor.

Price in Kenya (Approximate)

As of Friday, June 27, 2025, the approximate price for ASCOFF COUGH EXPECTORANT AND BRONCHODILATOR 100MLS in Kenya can range from Ksh 300 to Ksh 500 per bottle.

Note: Prices can vary between different pharmacies and retailers depending on stock, supplier, and any prevailing duties or taxes. It is advisable to check with specific pharmacies for the most current pricing.

Conclusion

ASCOFF COUGH EXPECTORANT AND BRONCHODILATOR 100MLS offers a comprehensive solution in Kenya for managing productive coughs and breathing difficulties associated with upper respiratory tract infections. Its multi-ingredient formulation, combining a bronchodilator (Salbutamol), a mucolytic (Bromhexine), an expectorant (Guaifenesin), and a soothing agent (Menthol), effectively loosens mucus, opens airways, and facilitates easier breathing.²⁷ While generally effective, it is crucial to adhere to the recommended dosage and precautions, especially given the presence of Salbutamol. Always consult a healthcare professional for guidance, particularly for children, individuals with pre-existing medical conditions, or if symptoms persist or worsen.